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To test if this mechanism was at play upon depleting GSH in the liver, we treated Gclc L-KO mice with T0901317, an LXR agonist

L'ablation de la vsicule biliaire (cholcystectomie) est recommande aprs rsolution de l'inflammation pour prvenir les rcidives

b , Uncoupling protein 1 (Ucp1)

Above the high-risk line (300 ug/mL at 4 hours) indicates a high risk of liver failure (massive ingestion), which may warrant even more aggressive therapy (discussed below)

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They dont know how to manage the side effects